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A review of controlled studies published in the June 2008 edition of the journal Cephalalagia supports the notion that anticonvulsants Depakote and Topamax are much more effective than placebo in preventing migraine attacks. The study also indicates that other anticonvulsants sometimes used for migraine prevention are no more effective than placebo.
Anticonvulsants in Migraine Prophylaxis
Diamox (acetazolamide), Klonopin (clonazepam), Lamictal (lamotrigine) and Sabril (vigabatrin) were no more effective than placebo in preventing migraine attacks. (Note: Vigabatrin has not been FDA approved for any purpose.) The study's authors said Neurontin (gabapentin) needs further study. They also suggested there is a great need for trials to compare the effectiveness of different anticonvulsants when used for migraine prevention.
Sources:
Medline Plus Drug Information: Acetazolamide Oral
Epilepsy.com: Introduction to Sabril
Technorati Tags: news, research, prevention, medication, depakote, topamax, depression, migraines, chronic illness, health, somebody heal me
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Content by Diana E. Lee.
1 comments:
Interesting news--thanks for linking to the study results.
I took Lamictal for a few weeks or months in 2004. Let us talk for a minute about how it didn't help my migraines. It did help me get swollen lymph nodes all over my body, esp. on my neck and shoulders. I was very lumpy.
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